Hard Mode in Sephiria (Root Decay) requires specific artifacts to survive. This guide covers the best defensive, offensive, and utility artifacts for Hard Mode stages, organized by tier.

S-Tier Hard Mode Artifacts

ArtifactCategoryWhy It's S-Tier
Magma OrbElementalCore of Plasma Judgment Staff build — essential for Stage 60
Thundercloud CompassElementalLightning chain trigger — makes the Plasma loop work
Explosion Proof VestDefensiveReduces trap damage — counters Machine Rebellion modifier
Neutralizer NoirComboEssential for poison builds — increases stack count
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A-Tier Hard Mode Artifacts

ArtifactUse Case
Oink Shaman's NecklaceElemental amplification — extends status durations
Lightning StoneLightning damage — good for Superconductor builds
Sword Training ManualCombat stat boost — general purpose
Charm of StrengthAttack boost — works with any weapon
Pouch of Black TeaPoison application — core of poison build
Golden Crown of ArroganceRisk/reward damage boost

Modifier-Specific Artifact Picks

Violent Claw (enemy damage up)

Stack Explosion Proof Vest + Slim Cushion + Robe of Yearning for maximum damage reduction.

Blood Feast (enemies heal on hit)

Use Magma Orb + Thundercloud Compass — the Plasma build deals so much damage that enemy healing can't keep up.

Tension (no potions in boss fights)

Equip Sapote Fruit (passive HP sustain) + White Crust Bread (passive regen). Pair with Endurance talent 20 for the revive.

Vertigo (fewer artifact choices)

Use Wisdom talent 10 (forced Unique artifacts) to mitigate reduced selection. Chalcedony Key provides extra reroll economy.

For the full artifact catalog, see our Artifact Database.

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Game data sourced from community gameplay and wikis. Game images © TEAM HORAY. Used under fair use.