The Destiny Inscription (運命の刻印) system is Sephiria's permanent progression meta. You spend Sapphire gems — earned inside dungeons — to unlock permanent upgrades that carry across all runs. The system also unlocks the Talent tree, which is your per-run skill allocation.
Destiny Inscription Categories
Event-Type Inscriptions
These unlock new features and mechanics:
| Inscription | Effect |
|---|---|
| Home Repair | Unlocks Talents system |
| Heavy Weapon Training | Unlocks Steel Greatsword |
| Sharp Weapon Training | Unlocks Dagger |
| Ranged Weapon Training | Unlocks Colossal Crossbow |
| Foreign Weapon Training | Unlocks Katana |
| Riley's Gift | Start each run with 1 Recovery Potion |
| Magic Workshop | +2 potion-only bag slots |
| Terrain Restoration | Unlocks Will talent tree |
| Hide-and-Seek | Unlocks Cunning talent tree |
| Basement | New costume appearance |
Status-Type Inscriptions
| Inscription | Effect |
|---|---|
| Talent Points | Grants permanent talent points (up to 30 total) |
| Travel Funds | Start each run with Leaf currency |
| Dice | Start each run with dice |
| Dice Acquisition | Gain 2 dice when defeating a boss |
| HP Recovery on Level Up | Recover HP when leveling up |
| HP Increase | Increase max HP permanently |
| MP Regeneration | Increase MP regen permanently |
| XP Drop Increase | Increase XP gained from kills |
| Expanding Bag | Increase bag slots permanently |
Item-Type Inscriptions
| Inscription | Effect |
|---|---|
| New Artifact | Unlock a new artifact in the pool |
| Bond Artifact | Unlock bond-type artifacts (special combo items) |
Other-Type Inscriptions
| Inscription | Effect |
|---|---|
| Rune (Stone Tablet) | Unlock runes — runes raise artifact levels permanently |
| Dice Conversion | Gain 1 dice when discarding item rewards |
| Fountain of Wishes | Unlock carry-in artifacts at run start |
| Box of Possibilities | Roll merchant items using Sapphire |
The 7 Talent Trees
Each talent point placed in a tree grants a base effect. At thresholds of 5, 10, and 20 points, you unlock additional milestone bonuses.
1. Anger (怒り) — Crit & Burst
| Threshold | Bonus |
|---|---|
| Base (per point) | +1% critical hit chance |
| 5 points | Critical damage +20% |
| 10 points | Boss & miniboss damage +10% |
| 20 points | Armor penetration +20% |
Best for: DPS builds, especially Greatsword and Crossbow crit builds. The 10-point boss damage bonus is excellent for Hard Mode.
2. Swift (迅速) — Attack Speed & Evasion
| Threshold | Bonus |
|---|---|
| Base (per point) | +1% attack speed |
| 5 points | Evasion +8, Dash +1 charge |
| 10 points | Dash recovery +20%, Weapon damage +8% |
| 20 points | Dash invincibility +0.1s, Weapon damage +15% |
Best for: Dagger and Katana builds. The dash invincibility at 20 points is essential for dodging Swift Claw modifier enemies.
3. Survival (生存) — HP & Bag Utility
| Threshold | Bonus |
|---|---|
| Base (per point) | +2 max HP |
| 5 points | Potions convert to random stat +1 |
| 10 points | Bag +3 slots |
| 20 points | Bag -12 (sacrifice), unlock Rune Imprint |
4. Endurance (忍耐) — Defense & Revive
| Threshold | Bonus |
|---|---|
| Base (per point) | +1 defense |
| 5 points | Start each run with a Base Rune |
| 10 points | HP regen when under 25% HP |
| 20 points | Revive once at 60% max HP (per run) |
Best for: Tension modifier (no potions in boss fights) — the revive at 20 points is a lifesaver. Also great for Violent Claw modifier runs.
5. Wisdom (知恵) — MP & Artifact Control
| Threshold | Bonus |
|---|---|
| Base (per point) | +1 MP regeneration |
| 5 points | MP absorb +5, Max MP +10 |
| 10 points | Forced Unique artifacts, Combo +2 per duplicate |
| 20 points | Free reroll +1 per item reward, XP +20% |
Best for: Staff builds, Vertigo modifier runs. The forced Unique artifacts at 10 points help mitigate reduced selection lines.
6. Will (意志) — Luck & Fountain
| Threshold | Bonus |
|---|---|
| Base (per point) | +1 luck |
| 5 points | Dice +2, Fountain +1 slot |
| 10 points | HP +15, MP +25 |
| 20 points | Fountain +4 slots |
Best for: Vertigo counter-play (Luck 10 mitigates selection penalties). Fountain of Wishes synergy — carry more artifacts into runs.
7. Cunning (機智) — HP, Evasion & Combo
| Threshold | Bonus |
|---|---|
| Base (per point) | +1 max HP, +0.5 evasion |
| 5 points | Bag +2 slots |
| 10 points | Item choice +1 |
| 20 points | Combo damage +7% per active combo |
Best for: Combo-heavy builds (Embers/Magitech/Curse). The 20-point bonus scales with the number of active combos — perfect for the Plasma build.
Recommended Talent Distributions
Plasma Judgment Staff Build
Wisdom 20 / Cunning 20 / Endurance 10 — Maximum combo damage and MP sustain. The free rerolls help find Magma Orb and Thundercloud Compass.
Greatsword Tank Build
Endurance 20 / Anger 10 / Swift 10 / Survival 10 — Defense and revive for Hard Mode, with enough crit to be a threat.
Poison Debuff Build
Cunning 20 / Wisdom 10 / Will 10 / Endurance 10 — Combo damage scaling with the poison build's multiple active combos.
Speedrun Build
Swift 20 / Anger 10 / Cunning 10 / Wisdom 10 — Maximum attack speed and crit for fast clears.
Destiny Inscription Priority for New Players
- Home Repair — Unlocks the Talent system. Do this first.
- Talent Points ×3 — Get at least 3 points to start feeling the effects.
- Heavy Weapon Training — Unlocks Greatsword for early progression.
- Riley's Gift — Free potion at start is a nice safety net.
- Expanding Bag — More inventory space for grid management.
- Fountain of Wishes — Carry-in artifacts for pre-planning builds.
- Rune — Unlocks rune imprint system for tablet permanence.
- Then focus on other weapon unlocks and Talent Points up to 30.
Data sourced from the Japanese Sephiria wiki (wikiwiki.jp/sephiria). Game images © TEAM HORAY.